Slide background
Department of Pharmaceutical Microbiology

Department of Pharmaceutical Microbiology

Pharmaceutical Microbiology, studies the properties of microorganisms that cause infections in humans, the diseases caused by microorganisms and microbiological methods for the diagnosis of these diseases. In addition, the production of antimicrobial agents and microbial products, cosmetics and pharmaceuticals microbiological quality control procedures, methods of sterilization-disinfection and general hygiene issues such as interest-enters the Pharmaceutical Microbiology. Our department is an interdisciplinary field of science in the field of Pharmaceutical Microbiology and aims to educate individuals such as pharmacists, basic scientists and researchers assimilated the basic concepts and applications in all areas of the profession. In addition, our department also aims to current research by following the developments closely in the field of Pharmaceutical Microbiology and Medical Microbiology serving public health and transfer the knowledge to the world of science, industry and the society in national and international platform, most effectively.

 Departmental Facilities

There are 2 laboratories (40m2 each) in our department. In these laboratories, there are available technical equipments and working conditions for performing classic microbiological culture studies, advanced molecular microbiological diagnosis and molecular epidemiological studies. In research laboratory, antimicrobial activity studies, nucleic acid amplification-based diagnostic and further typing methods such as PCR, PCR-RFLP, rt-PCR, DNA sequencing as well as immunochemical assay methods such as Westernblotting, Dot blotting and ELISA for the diagnosis and characterization of bacteria, fungi, viruses and parasites are applied successfully. In addition, our academic staffs are the project partners within a project established an infrastructure, advanced molecular diagnostic laboratory of the early diagnosis of cancer and miRNA-based cancer diagnostic studies conducted in Mersin University Research Center for Advanced Technology Education (MEITAM). Our department offers the opportunity to research and education on nanotechnology based high capacity Real-Time PCR system estabilished in this molecular diagnosis laboratory to our students.

 


Publications in International Scientific Journals(last two years)

2021
26. Gungor, S.; Guzel, S.; Ulger, M.; Kokdil, G. Chemical Composition and Antioxidant and Antimicrobialactivities of Turkish Endemic Trigonella rhytidocarpa Seeds. CHEMISTRY OF NATURAL COMPOUNDS, 2021, 57, 136-140.
http://dx.doi.org/10.1007/s10600-021-03298-x
25. ülger, M.; Tezcan ülger, S.; Oktay gültekin, E.; Yabalak, E.; Gülbudak, H.; Delialioğlu, N.; Gizir, A.; Aslan, G. Aloe vera (L.) Burm.f. ve Hypericum perforatum L. Yapraklarından Elde Edilen Bitki Ekstraktlarının İn vitro Antileishmanial Etkisi. KAFKAS UNIV VET FAK DERG, 2021, 27, 363-370.
http://dx.doi.org/10.9775/kvfd.2021.25633
24. Emre, G.; Dogan, A.; Haznedaroglu, M.; Senkardes, I.; Ulger, M.; Satiroglu, A.; Can emmez, B.; Tugay, O. An Ethnobotanical Study of Medicinal Plants in Mersin (Turkey). FRONT. PHARMACOL, 2021, 12, 664500-664500.
http://dx.doi.org/10.3389/fphar.2021.664500
2020
23. Vural, E.; Delialioğlu, N.; Tezcan ulger, S.; Emekdas, G.; Serin, M. Phenotypic and Molecular Detection of the Metallo-Beta-Lactamases in Carbapenem-Resistant Pseudomonas aeruginosa Isolates from Clinical Samples. KOWSAR MEDICAL INSTITUTE, 2020, 13, 0-0.
http://dx.doi.org/10.5812/jjm.90034
22. öksüz, Z.; üçbilek, E.; Serin, M.; Yaraş, S.; Temel, G.; Sezgin, O. Circulating vascular adhesion protein-1(VAP-1): a possible biomarker for liver fibrosis associated with chronic hepatitis B and C. SPRINGER SCIENCE AND BUSINESS MEDIA LLC, 2020, 3, 1-10.
http://dx.doi.org/10.1007/s42770-020-00379-x
21. Ağırtaş, M.; Cabir, B.; Yıldıko, .; özdemir, S.; Gonca, S. Synthesis, antioxidant, DNA cleavage and antimicrobial properties of phthalocyanine complexes bearing the poly-hydroxyl groups. CHEMICAL PAPERS, 2020, 1, 1-12.
http://dx.doi.org/10.1007/s11696-020-01432-7
20. Belveren, S.; Poyraz, S.; ülger, M.; Pask, C.; Döndaş, H.; Sansano, J. Synthesis, structure and bioactivity of a mononuclear octahedral [Prolinate2-Na(MeOH)4]−H+ complex. INORGANICA CHIMICA ACTA, 2020, 504, 119456-119456.
Publications_044.pdf
19. Kirik, F.; ülger, M.; Tezcan ülger, S.; Aslan, G. Association of cytokine gene polymorphisms with susceptibility to cutaneous leishmaniasis in a Turkish population. PARASITE IMMUNOL, 2020, 13, 12775-12775.
Publications_046.pdf
18. öksüz, Z.; üçbilek, E.; Serin, M.; Yaraş, S.; Temel, G.; Sezgin, O. Circulating vascular adhesion protein-1(VAP-1): a possible biomarker for liver fibrosis associated with chronic hepatitis B and C. SPRINGER SCIENCE AND BUSINESS MEDIA LLC, 2020, 51, 1757-1763.
http://dx.doi.org/10.1007/s42770-020-00379-x
17. Güzel, S.; ülger, M.; Kahraman, A. Chemical Composition and Some Biological Activities of Salvia longipedicellata Hedge Mericarps. CHEMISTRY OF NATURAL COMPOUNDS, 2020, 56, 788-792.
Publications_047.pdf
2019
16. Kaplan, E.; Gonca, S.; Kandemir, H.; Döğen, A.; Hilmioğlu-polat, S.; ılkit, M.; Tanaka, R.; Yaguchi, T.; Uhrlaβ, S. Genes Encoding Proteolytic Enzymes Fungalysin and Subtilisin in Dermatophytes of Human and Animal Origin: A Comparative Study. MYCOPATHOLOGIA, 2019, 184, 0-0.
http://dx.doi.org/10.1007/s11046-019-00367-2
15. Ergin, .; şengül, M.; Aksoy, L.; Döğen, A.; Sun, S.; Averette, A.; Cuomo, C.; Seyedmousavi, S.; Heitman, J. Cryptococcus neoformans Recovered From Olive Trees (Olea europaea) in Turkey Reveal Allopatry With African and South American Lineages. FRONTIERS MEDIA SA, 2019, 9, 1-10.
http://dx.doi.org/10.3389/fcimb.2019.00384
14. Binzet, R.; Binzet, G.; Gumus, I.; Turunc, E.; Solmaz, U.; Keskin, E.; Dogen, A.; Arslan, H. Chemical Composition and Antimicrobial Activity of Essential Oil and Various Extracts of Onosma sieheana Hayek Roots. INFORMA UK LIMITED, 2019, 1, 1-11.
http://dx.doi.org/10.1080/0972060X.2019.1600431
13. Kaplan, E.; Gonca, S.; Kandemir, H.; Döğen, A.; Hilmioğlu-polat, S.; ılkit, M.; Tanaka, R.; Yaguchi, T.; Uhrlaβ, S. Genes Encoding Proteolytic Enzymes Fungalysin and Subtilisin in Dermatophytes of Human and Animal Origin: A Comparative Study. SPRINGER SCIENCE AND BUSINESS MEDIA LLC, 2019, 1-12.
http://dx.doi.org/10.1007/s11046-019-00367-2
12. Kaplan, E.; Aktaş, D.; önder, .; Metin, B.; Döğen, A.; Oz, Y.; ılkit, M. Mating genotypes and susceptibility profiles of clinical isolates of Candida glabrata from Turkey. WILEY, 2019, 1, 1-5.
http://dx.doi.org/10.1111/myc.12945
11. Belveren, S.; Poyraz, S.; Pask, C.; ülger, M.; Sansano, J.; Ali döndaş, H. Synthesis and biological evaluation of platinum complexes of highly functionalized aroylaminocarbo-N-thioyl prolinate containing tetrahydropyrrolo[3,4-c]pyrrole-1,3(2H,3aH)-dione moieties. INORGANICA CHIMICA ACTA, 2019, 498, 119154-119154.
http://dx.doi.org/10.1016/j.ica.2019.119154
10. Guzel, S.; Ozay, Y.; Kumas, M.; Uzun, C.; Ozkorkmaz, E.; Yildirim, Z.; Ulger, M.; Guler, G.; Celik, A. Wound healing properties, antimicrobial and antioxidant activities of Salvia kronenburgii Rech. f. and Salvia euphratica Montbret, Aucher & Rech. f. var. euphratica on excision and incision wound models in diabetic rats. BIOMEDICINE & PHARMACOTHERAPY, 2019, 111, 1260-1276.
https://dx.doi.org/10.1016/j.biopha.2019.01.038
9. öksüz karaarslan, Z.; Serin, M.; Serin, A.; Sezgin, O.; Gonca, S. . MIKROBIYOLOJI BULTENI, 2019, 53, 156-169.
10.5578/mb.67796
8. Belveren, S.; Larrañaga, O.; Poyraz, S.; Döndaş, H.; ülger, M.; şahin, E.; Ferrándiz-saperas, M.; Sansano, J.; Gracia retamosa, D. From Bioactive Pyrrolidino[3,4-c]pyrrolidines to more Bioactive Pyrrolidino[3,4-b]pyrrolidines via Ring-Opening/Ring-Closing Promoted by Sodium Methoxide. SYNTHESIS, 2019, 51, 1595-1577.
10.1055/s-0037-1611356
7. Ergin, .; şengül, M.; Döğen, A.; Ilkit, M. Prediction of the Species Distribution of Cryptococcus neoformans Throughout Turkey . MIKROBIYOLOJI BULTENI, 2019, 53, 233-238.
10.5578/mb.67999
6. Metin, B.; Döğen, A.; Yıldırım, E.; De hoog, G.; Heitman, J.; ılkit, M. Mating type (MAT) locus and possible sexuality of the opportunistic pathogen Exophiala dermatitidis. ELSEVIER BV, 2019, 124, 29-38.
http://dx.doi.org/10.1016/j.fgb.2018.12.011
5. Tezcan ülger, S.; Kurnaz, N.; ülger, M.; Aslan, G.; Emekdaş, G. Serological Evidence of Rift Valley Fever Virus Among Humans in Mersin Province of Turkey. J VECTOR BORNE DIS, 2019, 56, 373-379.
Publications_042.pdf
4. öksüz, Z.; Serin, M.; Serin, A.; Sezgin, O.; Gonca, S. Düzeltme/Erratum. MIKROBIYOLOJI BULTEMIKROBIYOL BULNI, 2019, 53, 480-480.
Publications_017.pdf
3. Gemili, M.; Nural, Y.; Keles, E.; Aydiner, B.; Seferoglu, N.; Ulger, M.; Sahin, E.; Erat, S.; Seferoglu, Z. Novel highly functionalized 1,4-naphthoquinone 2-iminothiazole hybrids: Synthesis, photophysical properties, crystal structure, DFT studies, and anti(myco)bacterial/antifungal activity. JOURNAL OF MOLECULAR STRUCTURE, 2019, 1196, 536-546.
https://dx.doi.org/10.1016/j.molstruc.2019.06.087
2. şengül, M.; Kutlu, M.; Döğen, A.; Aksoy, L.; Gonca, S.; Ilkit, M.; Ergin, . Isolation of Cryptococcus neoformans from a Chesnut Tree (Castanea sativa), Denizli, Turkey . MIKROBIYOLOJI BULTENI, 2019, 53, 61-69.
10.5578/mb.67583
1. şengül, M.; Kutlu, M.; Döğen, A.; Aksoy, L.; Gonca, S.; Ilkit, M.; Ergin, . Isolation of Cryptococcus neoformans from a Chesnut Tree (Castanea sativa), Denizli, Turkey. MIKROBIYOLOJI BULTENI, 2019, 53 , 61-69.
Publications_005.pdf