Department of Pharmaceutical Biochemistry
Biochemistry is a branch of science that examines the chemical structure and functions of biological systems at the molecular level and is at the heart of health and life sciences. For this purpose, it is in close contact with many branches of science. Our department has been actively continuing its education and research activities since the foundation of the Faculty of Pharmacy.In addition to the comprehensive research training we offer in our laboratories in Master and Doctorate programs, theoretical and practical training is provided on advanced biochemistry, metabolism diseases, signal transmission, neurochemistry, hormones, proteins, lipoproteins, recombinant DNA techniques. The objectives of the master and doctorate programs are to provide and develop basic knowledge and laboratory skills in the field of biochemistry and Health Sciences. Our major research facilities include enzymology, oxidative stress, apoptosis, protein chemistry, hemoglobinopathies and molecular biology.
COMPLETED MASTER'S THESES
| Author (Graduation Year) | Thesis Title | Advisor |
| YANOOF ABDULWAHAB MOHAMMED ABDULLAH (2025) | Investigation of the biochemical properties of the Globularia anatolica plant | Prof. Serap YALIN
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| KHADIJAH AL DOS (2025) | Investigation of the bioactive potential of Haslea and Spirulina subsalsa | Prof. Serap YALIN
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| ELİF TOKU (2025) | Immobilization of urease onto cellulose nanocrystals | Prof. Serap YALIN
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| EBRU KUCUK (2023) | Effect of hesperidin loaded pH and temperature sensitive smart nanoparticles on breast cancer | Prof. Serap YALIN II. Advisor: Assoc. Prof. Metin YILDIRIM |
| EHSAN SAYEDALI (2023) | The role of lncrna h19 in the resistance of ovarian cancer cells to cisplatin therapy | Prof. Serap YALIN |
| SELDA SAGPAZAR (2022) | Investigation of the effect of cobalt oxide nanoparticles on liver in rats | Prof. Serap YALIN |
| AHMET YALTIR (2021) | The relationship between infection parameters from complete blood count and active lung tuberculosis | Prof. Serap YALIN |
| MERVE ERDEM (2025) | Investigation of the effect of ocimum basilicum extract on adhesion molecules and inflammation-related mirna expression levels | Prof. Ali Erdinc YALIN
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| ZEYNEP ZULAL DIKICI (2023) | Investigation of the effect of aronia (Aronia melanocarpa) on rats exposed to radiation | Prof. Ali Erdinc YALIN II. Advisor: Prof. Serap YALIN |
| DENIZ OGUZBEY (2021) | Biochemical characterization of hawthorn kernel oil | Prof. Ali Erdinc YALIN |
| HIBA LALOU (2021) | Study the effects of curcumin and naringenin on liver damage caused by copper nanoparticles | Prof. Ali Erdinc YALIN II. Advisor: Assoc. Prof. Metin YILDIRIM |
| KEMAL TOPAL (2021) | Determination of variations in genes encoding toll-like receptors in breast cancer cases | Prof. Ali Erdinc YALIN |
| ALDEN TUGCE UNLUGENC (2022) | Investigation of the effect of resveratrol on liver and kidney on experimental hyperthroid-conditioned rats | Prof. Necmiye CANACANKATAN II. Advisor: Asst. Prof. Serife Efsun ANTMEN |
| HILAL AVAN (2022) | Association between b-type natriuretic peptide gene SNP RS198389 polymorphism and atherosclerosis | Asst. Prof. Zeynep Nil UNAL |
| RANA HMAIDI (2025) | Investigation of TSC1/TSC2 and related genes in breast cancer | Asst. Prof. Serife Efsun ANTMEN |
| NAJWA DABOUL (2024) | Relati̇onshi̇p of transcri̇pti̇on factor srebp and i̇ts target genes involved i̇n li̇pogenesi̇s wi̇th endometri̇al cancer | Asst. Prof. Serife Efsun ANTMEN |
COMPLETED DOCTORAL DISSERTATIONS
| Author (Graduation Year) | Thesis Title | Advisor |
| YASEMIN APAK (2023) | Tryptophan metabolism, inflammation and oxidative stress in osteoarthritis patients | Prof. Serap YALIN |
| ERKAN ONER (2022) | Nitrile functionalized N-heterocyclic carbene precursors and carbene complex synthesis: Enzyme inhibition, anti-cancer activity and dna binding properties | Prof. Serap YALIN |
| HASAN OZ (2023) | Investigation of miRNAs that affect PI3K / AKT / mTOR signaling pathway in endometrial cancer | Prof. Necmiye CANACANKATAN II. Advisor: Asst. Prof. Serife Efsun ANTMEN |
| KEVSER ELCI (2023) | Investigation of expressions of mirna's associated with depression in patients with active tuberculosis | Prof. Necmiye CANACANKATAN |
| MERIH AKKAPULU (2024) | The relationship of acid sensing ion channels 1 (ASIC1) gene variations with coronary artery disease | Prof. Ali Erdinc YALIN |
| TULAY OZKAYA (2025) | Aronia melanocarpa herbal extracts in wound healing evaluation with in vitro studies | Asst. Prof. Zeynep Nil UNAL |
| Kemal AKKAYA (2024) | Investigation of the effects of cysteinyl leukotriene 1 receptor antagonists on lipopolysaccharide (lps)-induced inflammation in raw 264.7 macrophage | Asst. Prof. Zeynep Nil UNAL |
SEMINARS
2021/2022 Academic Year Spring Semester
| TOPIC OF THE SEMINAR | PRESENTER | DATE AND TIME | RESPONSIBLE FACULTY MEMBER |
| HIGH PERFORMANCE LIQUID CHROMATOGRAPHY | DENIZ OGUZBEY | 26.04.2022-12.00 | Prof. Ali Erdinc YALIN |
| PROTECTIVE EFFECT OF VITAMIN C ON THE ENDOTHELIAL LAYER | EFRA YENICERI | 27.05.2022-12.15 | Prof. Necmiye CANACANKATAN |
2022/2023 Academic Year Fall Semester
| TOPIC OF THE SEMINAR | PRESENTER | DATE AND TIME | RESPONSIBLE FACULTY MEMBER |
| APOPTOZIS | MERVE ERDEM | 27.12.2022-14.30 | Prof. Ali Erdinc YALIN |
2022/2023 Academic Year Spring Semester
| TOPIC OF THE SEMINAR | PRESENTER | DATE AND TIME | RESPONSIBLE FACULTY MEMBER |
| EFFECTS OF CHROMIUM ON DIABETIC PATIENTS | SIMA SHBERO | 30.05.2023-10.30 | Prof. Ali Erdinc YALIN |
| UREA CYCLE DISORDERS | YUNUS FIDAN | 30.05.2023-10.00 | Prof. Ali Erdinc YALIN |
| PROTEOMICS AND CRISPR-Cas9 | KHADIJAH AL DOS | 02.06.2023-13.00 | Prof. Serap YALIN |
| GENETIC POLYMORPHISMS AND MUTATIONS: EVALUATION OF THEIR ASSOCIATION WITH COLORECTAL CANCER RISK | KHALED ALSUBEEH | 01.06.2023-11.00 | Prof. Serap YALIN |
| NANOTECHNOLOGY: DRUG DELIVERY AND BIOMEDICAL APPLICATIONS | YANOOF ABDULURAHAB MUHAMMED ABDULLAH | 02.06.2023-11.00 | Prof. Serap YALIN |
| ENZYME IMMOBILIZATION | ELIF TOKU | 02.06.2023-10.00 | Prof. Serap YALIN |
| NEUROPATHOLOGY AND DETECTION METHODS OF ALZHEIMER'S DISEASE | NAJWA DABOUL | 26.05.2023-13.30 | Asst. Prof. S. Efsun ANTMEN |
| LYSOSOMAL STORAGE DISEASES | AYSE GUL SIHIR | 13.06.2023-18.00 | Asst. Prof. S. Efsun ANTMEN |
| GENERAL PROPERTIES AND ANTIOXIDANT EFFECTS OF MELATONIN | SULENUR CAGLAR GUNEY | 13.06.2023-15.30 | Prof. Necmiye CANACANKATAN |
| DIABETES MELLITUS | OMAR ABDULLAH AHMED OMAR AL-TAYEB | 20.06.2023-10.00 | Prof. Necmiye CANACANKATAN |
| BIOCHEMICAL IMPORTANCE OF MAGNESIUM | AYBUKE KORKMAZ | 20.06.2023-10.30 | Prof. Necmiye CANACANKATAN |
| POLYCYSTIC OVARY SYNDROME | SHAHEEN NAJDAT SAQI EMAMLY | 20.06.2023-11.00 | Prof. Necmiye CANACANKATAN |
2023/2024 Academic Year Fall Semester
| TOPIC OF THE SEMINAR | PRESENTER | DATE AND TIME | RESPONSIBLE FACULTY MEMBER |
| BIOCHEMICAL MECHANISMS OF ALZHEIMER'S DISEASE | MUSTAFA OKSUZ | 20.12.2023-10.00 | Prof. Necmiye CANACANKATAN |
| DISORDERS OF AMINO ACID METABOLISM | BAHAR ACAR | 20.12.2023-10.40 | Asst. Prof. S. Efsun ANTMEN |
| MIGRAIN | RANA HMAIDI | 29.12.2023-10.30 | Asst. Prof. S. Efsun ANTMEN |
| BIOCHEMICAL ROLES OF INTESTINAL MICROBIOME IN HUMAN HEALTH | MHD OSAMA BEIRA | 25.12.2023-13.00 | Asst. Prof. Zeynep Nil UNAL |
2024/2025 Academic Year Spring Semester
| TOPIC OF THE SEMINAR | PRESENTER | DATE AND TIME | RESPONSIBLE FACULTY MEMBER |
| HYDROGEN PRODUCTION METHODS AND APPLICATION AREAS | OZGE CAM | 16.05.2025-10.30 | Prof. Serap YALIN |
| METABOLIC SYNDROME | IBRAHIM UNAL | 16.05.2025-11.30 | Prof. Serap YALIN |
| EPIGENETIC MECHANISMS AND THEIR BIOCEMICAL EFFECTS | HULYA OZUDOGRU | 20.05.2025-14.30 | Prof. Serap YALIN |
| THE BIOCHEMISTRY OF TYPE 2 DIABETES TREATMENT APPROACHES AND NUTRITION | RENGIN AKSU | 20.05.2025-13.30 | Prof. Necmiye CANACANKATAN |
| THE PATH OF KINUREN | SUHEYLA EZGI YASAR | 23.05.2025-10.30 | Prof. Necmiye CANACANKATAN |
| THE RELATIONSHIP BETWEEN ADIPOKINES AND OBESITY | ZEYNEP ZULAL DIKICI | 23.05.2025-11.00 | Prof. Dr. Ali Erdinc YALIN |