Moleküler Mikrobiyoloji Anabilim Dalı
The Molecular Microbiology Graduate Program is an interdisciplinary program that started its educational activities in the 2018-2019 academic year. Our department consists of 9 faculty members from different disciplines (Medical Faculty Medical Microbiology, Medical Biology, Faculty of Pharmacy Pharmaceutical Microbiology, Faculty of Science Molecular Biology and Genetics, Faculty of Science Biotechnology Department). Our department is the first graduate program in this field in Turkey, and we are currently working on establishing a doctoral program. The aim of establishing this master's program is to support, plan, coordinate, and implement interdisciplinary research in molecular microbiology in response to the scientific and technological priorities of the developing and changing world. Through this program, we aim to provide a trained workforce in this field, which is a sub-discipline of microbiology, by implementing basic and advanced degree training programs, to produce scientists who will follow and apply developments in molecular microbiology, and to contribute to the medical and scientific community.
Our graduate program covers topics such as basic and clinical microbiology, molecular genetics, environmental, food, and industrial microbiology, biotechnology, pharmaceutical microbiology, immunology, virology, mycology, parasitology, zoonotic diseases, microbial informatics, and advanced techniques in molecular microbiology. Our students conduct their laboratory work in the laboratories of the Faculty of Medicine Medical Microbiology, Faculty of Pharmacy Pharmaceutical Microbiology, and MEÄ°TAM. Graduates of the Faculty of Science Biology Department, Molecular Biology and Genetics Department, Veterinary Faculty, Faculty of Medicine, Faculty of Dentistry, Faculty of Pharmacy, and Engineering Faculty Bioengineering Department who meet the conditions specified in the Mersin University Graduate Education and Training Regulation can apply to the program.
Son İki Yılda Uluslararası Dergilerde Yayınlanan Makaleler
2025
32. Oğultekin teneke, S.; Serin, M.; öksüz, Z.; Temel, G.; Yaraş, S.; üçbilek, E.; Sezgin, O. Circulating chemokine levels and receptor polymorphisms have potential as biomarkers for fibrosis stages in patients with chronic hepatitis C infection. MOLECULAR BIOLOGY REPORTS, 2025, 52, 12-.
10.1007/s11033-025-10244-5
2024
31. Kimyon, A.; çetinkaya, A.; Hallıoğlu, O.; Aras, N. The evaluation of the SMAD1 rs1016792 polymorphism and gene expression on pulmonary hypertension due to congenital heart disease in children: a preliminary study. NUCLEOSIDES, NUCLEOTIDES & NUCLEIC ACIDS, 2024, , 1-14.
30. Eras, N.; çetinkaya, A.; Giray, D.; Hallıoğlu, O.; Aras, N. Expression Profile of TGFB1 Gene in Pediatric Patients with Isolated Bicuspid Aortic Valve. PEDIATRIC CARDIOLOGY, 2024, 45, 1-6.
29. Kesim, B.; Tezcan ülger, S.; Aslan, G.; üstün, Y.; Eminsoy, A.; Küçük, M. Effects of Sequential Antimicrobial Phases on Root Canal Microbiome Dynamics in Two-Visit Treatment of Primary Apical Periodontitis: A Longitudinal Experimental Study. LIFE, 2024, 14, 1696-1696.
28. Kesim, B.; Tezcan ülger, S.; Aslan, G.; üstün, Y.; Avcı, A.; Küçük, M. Effects of Sequential Antimicrobial Phases on Root Canal Microbiome Dynamics in Two-Visit Treatment of Primary Apical Periodontitis: A Longitudinal Experimental Study. LIFE, 2024, 14, 1696-.
27. ülger, M. Design, synthesis, biological evaluation and docking analysis of pyrrolidine-benzenesulfonamides as carbonic anhydrase or acetylcholinesterase inhibitors and antimicrobial agents. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2024, 42, 3441-3458.
26. AktaÅŸ, D.; Kaplan, E.; Ergin, Ã.; Ilkit, M.; Döğen, A. Çevresel Örneklerde Cryptococcus Kolonizasyonunun ve EÅŸey Genotipinin AraÅŸtırılması. MIKROBIYOLOJI BÃœLTENI, 2024, 58, 39-48.
25. Binzet, G.; Turunç, E.; Binzet, R.; Döğen, A.; Arslan, H. Chemical composition and antimicrobial activity of essential oils and various extracts of endemic Onosma malatyana (Boraginaceae) from Anatolia. INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH, 2024, , -.
2023
24. Güran, M.; çakıral, K.; Teralı, K.; Kandemir, T.; şanlıtürk, G.; Meral öcal, M.; Nağıyev, T.; Köksal, F. Meropenem in combination with baicalein exhibits synergism against extensively drug resistant and pan-drug-resistant Acinetobacter baumannii clinical isolates in vitro. OXFORD UNIVERSITY PRESS (OUP), 2023, 81, 1-11.
23. Almatar, M.; Albarri, O.; Lakhal, R.; Meral öcal, M.; Var öngel, I.; Köksal, F. Bacterial pathogens: Potential source for antimicrobial peptides. BENTHAM SCIENCE PUBLISHERS LTD., 2023, 24, 1-16.
22. Kaya, H.; Ersoy, L.; ülger, M.; Bozok, T.; Aslan, G. Investigation of efflux pump genes in isoniazid resistant Mycobacterium tuberculosis isolates. INDIAN JOURNAL OF MEDICAL MICROBIOLOGY, 2023, 46, 1-5.
21. Kaya, H.; Ersoy, L.; ülger, M.; Bozok, T.; Aslan, G. Investigation of efflux pump genes in isoniazid resistant Mycobacterium tuberculosis isolates. INDIAN JOURNAL OF MEDICAL MICROBIOLOGY, 2023, 46, 100428-.
20. Saleh, L.; Altıntaş, B.; Filiciotto, L.; Zorlu, Y.; Luque, R.; ülger, M.; Döndaş, H.; Altug, C. Structural assessment of novel spiro-naphthalene-1.2'-[1,3,4]oxadiazol-4-ones prepared under batch and flow chemistry with a concise antifungal and anti(myco)bacterial activity. TETRAHEDRON, 2023, 131, 133231-133231.
19. Poyraz, S.; Dondas, H.; Sansano, J.; Belveren, S.; Yamalı, C.; Ulger, M.; Yaktubay dondas, N.; Saglık, B.; Pask, C. N-Benzoylthiourea-pyrrolidine carboxylic acid derivatives bearing an imidazole moiety: Synthesis, characterization, crystal structure, in vitro ChEs inhibition, and antituberculosis, antibacterial, antifungal studies. JOURNAL OF MOLECULAR STRUCTURE, 2023, 1273, 134303-134303.
18. ErdoÄŸan eliuz, E.; Everest, Z.; Serin, M. Antimicrobial activity of Stachys rupestris Montbret et Aucher ex Benth. and inactivation of the pathogens inoculated on lab-made skin by the essential oil. INFORMA UK LIMITED, 2023, 33, 1749-1759.
17. Eroğlu, P.; Civaner, M.; Doğan çalhan, S.; ülger, M.; Binzet, R. Potential Biochemical Properties of Endemic Onosma mutabilis. ACTA CHIMICA SLOVENICA, 2023, 70, 196-203.
16. özgür, D.; Ersoy, L.; ülger, M.; Tezcan ülger, S.; Aslan, G. Birinci Seçenek Antitüberküloz İlaçlara ve Verapamil Kombinasyonuna Maruz Bırakılan Dirençli Mycobacterium tuberculosis Kompleks Klinik İzolatlarındaki Efluks Pompa Genlerinin Araştırılması. MIKROBIYOL BUL, 2023, 57, 207-219.
15. Yalçın özkat, G.; Ersan, R.; ülger, M.; Tezcan ülger, S.; BurmaoÄŸlu, S.; Yıldız, Ä.; Algül, Ã. Design, synthesis, and computational studies of benzimidazole derivatives as new antitubercular agents. JOURNAL OF BIOMOLECULAR STRUCTURE AND DYNAMICS, 2023, 41, 2667-2686.
14. Yaşar, N.; Tezcan ülger, S.; ülger, M.; Arslantürk, A.; Aslan, G.; Köksal, F. Etambutole Dirençli ve Duyarlı Mycobacterium tuberculosis Kompleksi Klinik İzolatlarında embA, embB ve embC Gen Bölgesi Mutasyonları. MIKROBIYOL BUL, 2023, 57, 45-59.
13. Yaşar, N.; Tezcan ülger, S.; ülger, M.; Arslantürk, A.; Aslan, G.; Köksal, F. [The Mutations on embA, embB and embC Gene Region in Ethambutol-Resistant and Susceptible Clinical Mycobacterium tuberculosis Complex Isolates].. MIKROBIYOLOJI BULTENI, 2023, 57, 45-.
12. Yamalı, C.; Sevin, S.; Nenni, M.; Tuğrak sakarya, M.; Uyar, R.; Aygül, A.; ülger, M.; Ilhan, R.; Levent, S. Design, synthesis, and assessment of pharmacological properties of indole-based fluorinated chalcones and their benzenesulfonamide analogs. CHAMICAL PAPERS, 2023, 77, 7903-7918.
11. Gürer giray, B.; Aslantürk, A.; şimşek, H.; özgür, D.; Kılıç, S.; Aslan, G. Determination of Genetic Diversity of Multidrug-Resistant Mycobacterium Tuberculosis Strains in Turkey Using 15 Locus MIRU-VNTR and Spoligotyping Methods. PATHOGENS AND GLOBAL HEALTH, 2023, 117, 85-91.
10. Yalçın özkat, G.; Ersan, R.; ülger, M.; BurmaoÄŸlu, S.; Yıldız, Ä.; Algül, Ã. Design, synthesis, and computational studies of benzimidazole derivatives as new antitubercular agents.. J BIOMOL STRUCT DYN, 2023, 27, 995-1004.
9. Kesim, B.; Tezcan ülger, S.; Aslan, G.; Cudal, H.; üstün, Y.; Küçük, M. Amplicon-based next-generation sequencing for comparative analysis of root canal microbiome of teeth with primary and persistent/secondary endodontic infections.. CLINICAL ORAL INVESTIGATIONS, 2023, 27, 995-.
8. Poyraz, S.; Döndaş, H.; Sansano, J.; Belveren, S.; Yamalı, C.; ülger, M.; Döndaş, N.; Sağlık, B.; Pask, C. N-Benzoylthiourea-pyrrolidine carboxylic acid derivatives bearing an imidazole moiety: Synthesis, characterization, crystal structure, in vitro ChEs inhibition, and antituberculosis, antibacterial, antifungal studies. JOURNAL OF MOLECULAR STRUCTURE, 2023, 1273, -.
7. Barçın, T.; Haj ersan, R.; Alagöz, M.; Döğen, A.; Burmaoglu, S.; Algül, Ã. Deep learning approach to the discovery of novel bisbenzazole derivatives for antimicrobial effect. ELSEVIER BV, 2023, 1295, -.
6. öksüz, Z.; Gragnani, L.; Lorini, S.; Temel, G.; Serin, M.; Zignego, A. Evaluation of Plasma miR-17-5p, miR-24-3p and miRNA-223-3p Profile of Hepatitis C Virus-Infected Patients after Treatment with Direct-Acting Antivirals. MDPI AG, 2023, 13, -.
5. Saleh, L.; Altıntaş, B.; Filiciotto, L.; Zorlu, Y.; Luque, R.; ülger, M.; Döndaş, H.; Altuğ, C. Structural assessment of novel spiro-naphthalene-1.2- [1,3,4]oxadiazol-4-ones prepared under batch and flow chemistry with a concise antifungal and anti(myco)bacterial activity. TETRAHEDRON, 2023, 131, -.
4. Turunç, E.; Karaman, O.; Döğen, A.; Binzet, R. Green synthesis of graphene quantum dot- and its electrochemical, antioxidant and antimicrobial activities. ELSEVIER BV, 2023, 299, -.
3. Metin, D.; Hilmioğlu polat, S.; Döğen, A.; Palamar onay, M. Fungal Keratitis and Corneal Perforation as a Rare Complication of Corneal Collagen Cross-Linking Treatment. OVID TECHNOLOGIES (WOLTERS KLUWER HEALTH), 2023, 42, -.
2. Kaya, H.; Ersoy, L.; ülger, M.; Bozok, T.; Aslan, G. Investigation of efflux pump genes in isoniazid resistant Mycobacterium tuberculosis isolates. INDIAN JOURNAL OF MEDICAL MICROBIOLOGY, 2023, 46, -.
1. ünal, N.; Karaman, O.; Döğen, A.; Binzet, R. Investigation of the Chemical Composition, Antimicrobial, and Antioxidant Activity of Endemic Onosma halophila Boiss. & Heldr.. SPRINGER SCIENCE AND BUSINESS MEDIA LLC, 2023, 80, -.